Helicobacter pyloriinfection in Mongolian gerbils does not initiate hematological diseases
نویسندگان
چکیده
منابع مشابه
Oxidative DNA Damage Response in Helicobacter pylori-Infected Mongolian Gerbils
Helicobacter pylori (H. pylori) induced DNA damage which may be related to gastric cancer development. The DNA damage response coordinates DNA repair, cell-cycle transition, and apoptosis through activation of DNA damage response molecules. The damaged DNA is repaired through non-homologous end joining (NHEJ) or homologous recombination (HR). In the present study, we investigated the changes of...
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Helicobacter pylori is classified by IARC/WHO as a definite human gastric carcinogen, despite "inadequate experimental evidence." To obtain direct evidence concerning this relationship, we investigated the histopathological findings of gastric mucosa using a model of H. pylori infection in Mongolian gerbils. The animals were challenged p.o. with H. pylori ATCC-43504 and sacrificed at 6, 12, and...
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Background: Helicobacter pylori infection and non-steroidal anti-inflammatory drugs are two major causes of gastric ulceration but interactions between H pylori and these drugs in gastric mucosal injury are unclear. Aims: We studied the influence of experimental H pylori infection on gastric mucosal injury induced by aspirin. Subjects: Male Mongolian gerbils free of specific pathogens were used...
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Ammonia is one of the important toxins produced by Helicobacter pylori (H. pylori), the major cause of peptic ulcer diseases. We examined whether glutamine or marzulene (a gastroprotective drug containing 1% sodium azulene and 99% glutamine) protects the gastric mucosa against H. pylori in vivo and investigated the mechanism underlying glutamine-induced mucosal protection against ammonia in gas...
متن کاملLipid Profile in Subjects with Helicobacter pyloriInfection
Background and Objectives: Helicobacter pylori cause a chronic gastric infection, and may cause extra gastrointestinal disease. The association between H. pylori infection and serum lipid profiles is still controversial. The aim of this study was to investigate any possible relationship between H. pylori infection and lipid levels. Materials and Methods: The subj...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2014
ISSN: 1007-9327
DOI: 10.3748/wjg.v20.i34.12308